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Dr Shapiro has had several patients try the HCG diet and complain of hair loss months later. This may well be because HCG increases testosterone levels and consequently contributes to hair loss. At the same time, there is no evidence it causes weight loss. The Federal Government has issued warning letters to seven companies producing the product.

The action of HCG is virtually identical to that of pituitary LH (Luteinizing Hormone). LH acts as a "thermostat" for testosterone control. As the testicles produce testosterone, levels in circulation rise. Once these levels reach a certain point, the pituitary will decrease secretion of LH and the signal to the testicles to produce testosterone is diminished. As testosterone production decreases, the pituitary will sense the drop and will resume secretion of LH.

Also see this article.

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